It was founded by a London Physician who was named Edward Alfred Cockayne(1880-1956)
This occurs rarely and it has two types: Cockayne1(A) or Cockayne2(B) and its a recessive heterogeneous
Usually occurs during birth or happens within first year of kids life. Children Usually don't live till adolescence but if they get lucky they will live till they are early adults(12).(if death occurs)
This disease can only be inherited by his/her parents. This happens when Genetic material gets damaged by ultra radiation. They cannot repair this because the DNA is damaged.
It causes premature aging. The person inherits two mutant genes, one from each parent. No genotype is known for this disease.
Chromosome Number: 5
GENES: mutations in the ERCC6 and ERCC8 genes cause Cockayne Syndrome
These two genes help with the repair of DNA. If any of these are altered the process will not happen rapidly. As a result to that the DNA accumulates that leads to impaired cell functions and eventually, cell death. Increasing in cell death will lead to Cockayne Syndrome such as premature aging.
Edward Alfred Cockayne
Other Names:
CS
dwarfism-retinal atrophy-deafness syndrome
progeria-like syndrome
progeroid nanism
Symptoms:
Pinched, Narrow face and beaked nose
Small head for body size
Mental Retardation
Sensitivity to sunlight
Short stature, Hunched back
Tremors, jerky movement, difficulty walking
But the symptoms do not show right away
How can it be treated?:
There is no cure for this disease all they can do is improve their life. They must protect them selves from sunlight with clothing or sunscreen to prevent cell damage. Adults can Home treat the child to help them with their behavior and with their medical disease.
Symptoms 2:
Unable to gain weight
Grow at unexpected rate
Impaired Development of the Nervous System
Abnormal reaction to sunlight
Hearing loss
Eye abnormalness
Severe tooth decay
Problems with internal organs
There are 53 known symptoms for this disease
Occurrence:
1 case for every 250,000 births
This disease effects less then 200,000 people in the USA population and effects 1-2000 people in Europe
Cockayne Syndrome:
It was founded by a London Physician who was named Edward Alfred Cockayne(1880-1956)
This occurs rarely and it has two types: Cockayne1(A) or Cockayne2(B) and its a recessive heterogeneous
Usually occurs during birth or happens within first year of kids life. Children Usually don't live till adolescence but if they get lucky they will live till they are early adults(12).(if death occurs)
This disease can only be inherited by his/her parents. This happens when Genetic material gets damaged by ultra radiation. They cannot repair this because the DNA is damaged.
It causes premature aging. The person inherits two mutant genes, one from each parent. No genotype is known for this disease.
Chromosome Number: 5
GENES: mutations in the ERCC6 and ERCC8 genes cause Cockayne SyndromeThese two genes help with the repair of DNA. If any of these are altered the process will not happen rapidly. As a result to that the DNA accumulates that leads to impaired cell functions and eventually, cell death. Increasing in cell death will lead to Cockayne Syndrome such as premature aging.
Other Names:
Symptoms:
How can it be treated?:
There is no cure for this disease all they can do is improve their life. They must protect them selves from sunlight with clothing or sunscreen to prevent cell damage. Adults can Home treat the child to help them with their behavior and with their medical disease.Symptoms 2:
- Unable to gain weight
- Grow at unexpected rate
- Impaired Development of the Nervous System
- Abnormal reaction to sunlight
- Hearing loss
- Eye abnormalness
- Severe tooth decay
- Problems with internal organs
- There are 53 known symptoms for this disease
Occurrence:1 case for every 250,000 births
This disease effects less then 200,000 people in the USA population and effects 1-2000 people in EuropeReferences:
QUESTIONS: